Raw Thermosalinograph (TSG) data for the 2016 West Coast Cetacean Cruise. The survey operated on the shelf and slope regions off the west coast of South Africa, between Area 1 (Dassen Island, 18.23669, -33.457 and Groenriviermond, 17.52061, -30.8277) and Area 2 (North-East Robben Island and Cape Point). This cruise was undertaken for data collection as part of a collaborative project led by the Department of Environmental Affairs (DEA) in collaboration with the Whale Unit, Mammal Research Institute of the University of Pretoria, Department of Agriculture, Forestry and Fisheries (DAFF), National Oceanic and Atmospheric Administration (USA), Aqualie Institute (Brazil) and Oregon State University (USA). The greater programme is titled "Large whale research: genetic relatedness, stock identification, abundance, feeding and migratory behavious". The large whale research programme has two components, the east coast and west coast components. This cruise focused on the west coast humpback whales.